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The latex of Euphorbia tirucalli L. (Euphorbiaceae) is used as an ointment in rheumatism, asthma, earache, cough, toothache and warts in traditional medicine[7]. It is also used for skin tumors and syphilis ulcers[2]. However, Euphorbia tirucalli L has been associated with Burkitts lymphoma and thought to be a cofactor of the disease rather than a treatment[5,6]. A biopolymeric fraction with anti-arthritic activity has been isolated from Euphorbia tirucalli L. It has particularly been demonstrated that this fraction induces dose dependent antiarthritic activity and in vivo immunomodulatory capacity being a major component in inhibiting arthritis[1]. In Tunisia, where Euphorbia tirucalli L. is a ornamental garden plant, the latex is locally used in popular medicine as anti-inflammatory drug especially in skin eczema. Hence, the present work was undertaken to test whether the plant latex possesses an anti-inflammatory activity in animals. MATERIALS AND METHODS
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